How CRISPR Works |
Title: Should CRISPR Scientists Play God?
Author: Ted Peters Abstract: Will CRISPR usher in a new era of Promethean overreach? CRISPR makes gene editing widely available and cheap. Anti-play-god bioethicists fear that geneticists will play god and precipitate a backlash from nature that could be devastating. In contrast to the anti-play-god bioethicists, this article recommends that laboratory science invoke the Precautionary Principle: pause at the yellow caution light, but then with constant risk-assessment proceed ahead. |
Title: Are We Closer To Free Market Eugenics? The CRISPR Controversy
Author: Ted Peters Abstract: Might the 2018 birth of two designer babies in China write the opening paragraph for the next chapter in the history of eugenics? The worldwide scientific community has tacitly put a moratorium on human clinical application of CRISPR gene editing, waiting until unknown risks can become known. But this ethical agreement has been breached, and calls are now being heard for more rigorous regulations. Perhaps religious and spiritual leaders can join the bioethical chant: the yellow light of caution is flashing. |
Title: Five myths about gene editing
Author: Bonnie Rochman Abstract: CRISPR's breakthrough made headlines. But are we ready to engineer designer babies? |
Title: NIH Director's Blog
Source: NIH Abstract: Francis S. Collins, M.D., Ph.D., the 16th Director of NIH, posts multiple articles about CRISPR. |
Title: CRISPR Technology: A New Approach To Eradicating Borrelia
Author: Dr. Chase Beisel Abstract: Dr. Chase Beisel was recognized earlier this year with one of Bay Area Lyme Foundation’s prestigious Emerging Leader Awards. This honor is in recognition of and support for his lab‘s novel work exploring CRISPR technology as a potential treatment for Lyme infections. |
Title: A collection of CRISPR articles in the journal Nature
Source: Nature Abstract: Researchers the world over are fast adopting CRISPR-Cas9 to tinker with the genomes of humans, viruses, bacteria, animals and plants. Nature brings together research, reporting and expert opinion to keep you abreast of the frontiers of gene editing. |
Title: A collection of CRISPR articles in the magazine Science
Source: Science Abstract: Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable. At least one group has already used CRISPR on human embryos, sparking calls for a moratorium on similar work and an international summit at the end of 2015 to discuss the science and ethics of human gene editing. Meanwhile, CRISPR is making it much easier to generate genetically modified animals and plants, creating new regulatory issues that scientists, agencies, politicians, and, ultimately, society must address. |
Title: A collection of CRISPR articles in the magazine Wired
Source: Wired |
Title: When DNA is not Destiny
Author: Sharon Begley Source: Newsweek |
Title: Rewriting the Code of Life
Author: Michael Specter Source: The New Yorker Abstract: Through DNA editing, researchers hope to alter the genetic destiny of species and eliminate diseases. |